Table 5 Univariate and multivariate Cox regression of FoxM1 for overall survival in glioma
From: Akt/FoxM1 signaling pathway-mediated upregulation of MYBL2 promotes progression of human glioma
| Â | OS | |||
|---|---|---|---|---|
Variable | Univariate analysis | Multivariate analysis | ||
| Â | HR (95% CI) | P-value | HR (95% CI) | P-value |
Age (year) | ||||
 <45 vs. ≥45 | 0.874 (0.488-1.567) | 0.652 | 0.964 (0.528-1.761) | 0.905 |
Gender | ||||
 Female vs. male | .964 (0.573 -1.622) | 0.889 | 1.010 (0.585-1.744) | 0.971 |
Clinical Stage | ||||
 III-IV vs. I-II | 0.297 (0.172-0.514) | <0.001 | 0.347 (0.188-0.642) | <0.05 |
Tumor Location | ||||
 Parietal vs. Frontal | 0.708 (0.358-1.398) | 0.32 | 1.068 (0.465-2.454) | 0.876 |
 Temporal vs. Frontal | 0.852 (0.474-1.533) | 0.594 | 1.170 (0.589-2.321) | 0.654 |
 Others vs. Frontal | 1.653 (0.812-3.364) | 0.166 | 1.425 (0.651-3.116) | 0.3754375 |
FoxM1 Expression | ||||
 Low vs. high | 0.336 (0.187-0.602) | <0.001 | 0.391 (0.196-0.779) | <0.05 |