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Table 1 The correlation between stathmin expression and clinical characteristics in OSCC

From: Stathmin is overexpressed and regulated by mutant p53 in oral squamous cell carcinoma

Characteristics

Patients (%)

Stathmin score

parametric test value

P value

Mean

SEM

Gender

 Male

35(58.3)

151.6

14.1

t = 1.189

0.239

 Female

25(41.7)

126.8

14.7

Age

  < 60 years

34(56.7)

143.2

12.4

t = 0.218

0.828

  ≥ 60 years

26(43.3)

138.7

17.7

T stage

 T1

17(28.3)

145.6

21.5

F = 0.039

0.990

 T2

19(31.7)

142.6

19.7

 T3

8(13.3)

136.3

29.8

 T4

16(26.7)

137.5

16.8

N stage

 cN0

41(68.3)

137.9

12.0

t = −0.470

0.640

 cN+

19(31.7)

148.4

20.0

TNM stage

 I/II

28(46.7)

132.7

14.7

t = −0.775

0.441

 III/IV

32(53.3)

148.8

14.5

Pathologic differentiation

 Well

30(50.0)

100.8

10.3

F = 14.757

< 0.001 *

 Moderately

22(36.7)

162.5

17.2

 poorly

8(13.3)

234.4

18.6

Smoking status

 Yes

21(35.0)

143.8

15.6

t = 0.181

0.857

 No

39(65.0)

139.9

13.6

Alcohol use

 Yes

15(25.0)

128.7

19.3

t = −0.702

0.486

 No

45(75.0)

145.4

12.2

  1. *Stathmin immunohistochemical scores correlated significantly with pathological differentiation grades, a poorer pathological differentiation grade indicated a higher staining score