TY - JOUR AU - Gu, Yixue AU - Zhang, Zhijie AU - Yin, Jiang AU - Ye, Jiahui AU - Song, Yin AU - Liu, Hao AU - Xiong, Yan AU - Lu, Minying AU - Zheng, Guopei AU - He, Zhimin PY - 2017 DA - 2017/08/31 TI - Epigenetic silencing of miR-493 increases the resistance to cisplatin in lung cancer by targeting tongue cancer resistance-related protein 1(TCRP1) JO - Journal of Experimental & Clinical Cancer Research SP - 114 VL - 36 IS - 1 AB - The potential mechanisms regarding how methylation of microRNA(miRNA) CpG Island could regulate cancer cell chemo-resistance remains unclear. This study aims to explore the epigenetic dysregulation mechanism of miRNA-493 and the ability to modulate lung cancer cell chemotherapy resistance. SN - 1756-9966 UR - https://doi.org/10.1186/s13046-017-0582-5 DO - 10.1186/s13046-017-0582-5 ID - Gu2017 ER -