Fig. 3
The effect of miR-493 on the sensitivity of lung cancer cells to cisplatin in nude mouse xenograft model. a and b, A549 and A549/DDP cells stably expressing miR-493 or the control was injected subcutaneously into the right flank of each nude mouse. The tumor growth curves and tumor inhibited rate were shown. The arrows indicated sites were the start treatment time with cisplatin or saline. Significant differences are indicated, (*, P < 0.05). c Representative images show ISH (red staining as nucleus and blue staining as miR-493 level) staining of the miR-493 tumors (×200) generated in nude mice and immunohistochemistry staining using TCRP1 and Ki67 antibodies on these tumors (×200)