Skip to main content
Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis

Fig. 1

The inhibition of J-4 on PKCζ activity and melanoma cells viability. (a) Molecular structure of J-4. (b) The inhibitory effect of J-4 on PKCζ activity evaluated by the Z’-LYTE™ KINASE ASSAY KIT-SER/THR 7 PEPTIDE kit. (c and d) The cell viability of A375 (c) and B16-F10 (d) were slightly affected by a 24-h treatment of J-4, Celecoxib (25 μM) or their combination measured by MTT assay. * P < 0.05

Back to article page