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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods

Fig. 4

Targeted NGS to detect DNA rearrangements from clincal specimens. (a) 7 FFPE resection specimens with ALK fusions identified by IHC were further analyzed by targeted NGS. The results were shown on the table. ALK fusion in sample 3D-65 was further confirmed by FISH (b). (c) 11 lung adenocarcinoma FFPE specimens that are positive in ALK fusions by targeted NGS were further analyzed by IHC. The results were summarized in the left table. ‘+’ represents positive ALK expression detected by IHC. Representative microscopical results of ALK expression from high to low are shown on the right panel

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