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Table 1 Clinical characteristics of the 211 colon cancer patients according to High or Low miR-19b-3p

From: miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses

Variable Total (n = 211) miR-19b-3p expression P value
   Low (n = 115) High (n = 96)  
Age
  < 65 y 89 47 42 0.721
  ≥ 65 y 122 68 54  
Gender
 Male 72 45 27 0.637
 Female 139 70 69  
Location
 Left 148 77 71 0.521
 Others 63 38 25  
T stage
 T1 + T2 17 9 8 0.764
 T3 + T4 194 106 88  
N stage
 N0 115 80 35 <0.001*
 N1 + N2 96 35 61  
AJCC stage
 I + II 114 86 28 <0.001*
 III + IV 97 29 68  
Histologic grade
 Well Differentiated 104 66 38 0.032*
 Poorly differentiated 107 49 58  
Venous & Lymphatic invasion
 No 197 110 87 0.247
 Yes 14 5 9  
Peritoneal Dissemination
 Absent 184 97 87 0.359
 Present 27 12 15  
Liver Metastsis
 Negative 164 96 68  
 Positive Multinodular 47 8 39 <0.001*
  1. P value are based on chi-square test
  2. AJCC: American Joint Committee on Cancer
  3. *P < 0.05 was considered significant