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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/β-catenin signaling

Fig. 6

Kindlin-2 promotes epithelial-mesenchymal transition in HCC cells. a Kindlin-2 knockout leads to upregulated expression of the epithelial marker E-cadherin in MHCC97H cells, while ectopic Kindlin-2 expression induced downregulated expression of E-cadherin in SMMC7721 cells. However, Kindlin-2 knockdown does not change the expression of E-cadherin in LM3 cells. b Knockout or knockdown of Kindlin-2 results in the downregulation of the mesenchymal markers vimentin, N-cadherin and Snail, while ectopic Kindlin-2 expression causes the opposite results in SMMC7721 cells

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