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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: β-catenin-mediated YAP signaling promotes human glioma growth

Fig. 2

Down-regulation of YAP inhibits intracranial glioma growth in vivo. a HE staining of tumors derived from scramble and shYAP cells. b Quantitative analysis of the tumor volume. c Kaplan-Meier curve of scramble and shYAP mice showed a clear survival advantage for YAP down-regulation (n = 6; P < 0.05, determined using log-rank test). d & e The number of metaphase cells was counted per 20 high-power fields (d, right: amplified images) and quantified (e). Scale bar: 20 μm. f & g Ki67 positive cells were determined by Ki67 staining. Scale bar: 50 μm. * P < 0.05, ** P < 0.01

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