Fig. 4
From: β-catenin-mediated YAP signaling promotes human glioma growth
YAP modulates the subcellular location of β-catenin. a & b The expression and subcellular location of β-catenin (a) and active-β-catenin (b) were assessed by immunofluorescence in YAP down-regulation or over-expression cells. Scale bar 50 μm. Inset showed the amplified images. c-f Quantification results of the percentage of cells with nuclear β-catenin (c & e) or active-β-catenin (d & f) in U251 and U87 cells. * P < 0.05, ** P < 0.01, *** P < 0.001. g & h Subcellular location of β-catenin or active-β-catenin was detected by using cellular fractionation and immunoblotting. Histone and GAPDH were used as nuclear and cytoplasm loading control respectively