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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells

Fig. 1

Effect of IL-27 on surface HLA class I and PD-L1 expression in human SCLC cells. Cytofluorimetric analysis of membrane HLA class I (a) or PD-L1 (b) expression in five SCLC cell lines, cultured in the presence of medium (baseline), IL-27 or IFN-γ (induced), for 48 h. Isotype-matched Ig control is indicated (ctrIg). Numbers in brackets represent Median Fluorescence Intensity (MFI) values calculated as median anti-HLA class I (W6/32), or anti-PD-L1 mAb minus median Ig control

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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