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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells

Fig. 4

Expression of IL-27R subunits in IL-27-responsive (NCI-N592) and IL-27-non-responsive (NCI-H146) SCLC cell lines. a Cytofluorimetric analysis of surface IL-27Rα/WSX1 and GP130 receptor chain expression in IL-27-responsive (NCI-N592) and non-responsive (NCI-H146) SCLC cell lines. Isotype-matched Ig control is also shown (ctrIg). Numbers in brackets represent MFI values, calculated as above. b QRT-PCR analysis of IL-27Rα (IL27RA) and GP130 (IL6ST) receptor chain mRNA expression in IL-27-responsive (NCI-N592) and non-responsive (NCI-H146, dark histogram) SCLC cell lines. Data are expressed as 1/ΔCT relative to POLR2A housekeeping gene. Error bars represent SD in one representative experiment out of two with consistent data

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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