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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: PAK5-mediated phosphorylation and nuclear translocation of NF-κB-p65 promotes breast cancer cell proliferation in vitro and in vivo

Fig. 2

The effect of PAK5 on breast cancer cells proliferation. a CCK-8 cell proliferation assays after PAK5 overexpression in BT549 and MDA-MB-231 cells. b CCK-8 cell proliferation assay after PAK5 knockdown in BT549 and MDA-MB-231 cells. c Effects of PAK5 overexpression on the cell cycle of breast cancer cells. The percentage of G1 population cells was measured by flow cytometry after PAK5 overexpression in BT549 and MDA-MB-231 cells. d Effects of PAK5 silencing on cell cycle analysis of BT549 and MDA-MB-231 cells. The percentage of cells at G1 stage was calculated using ModFit LT 3.0 software. Data are presented as mean ± SD for three independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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