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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: PAK5-mediated phosphorylation and nuclear translocation of NF-κB-p65 promotes breast cancer cell proliferation in vitro and in vivo

Fig. 3

Impact of PAK5 on the expression of cell cycle regulatory proteins. a, b Western blot analysis of the PAK5 gene overexpression and silencing on Myc, PAK5, Cyclin D1, Cyclin D3, Cyclin A, Cyclin A1, Cyclin B1 and Cyclin B3 in BT549 and MDA-MB-231 cells. c, d Western blot analysis of the PAK5 gene overexpression and silencing on p21 and p27 in BT549 and MDA-MB-231 cells. Data are shown as mean ± SD for three independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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