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Fig. 10 | Journal of Experimental & Clinical Cancer Research

Fig. 10

From: YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer

Fig. 10

G-4 (10 μM) changed the expression of downstream effectors. a Cells were treated with G-4 for 24 h and expressions of CTGF, Cyr61, MCL, MDR, Survivin, Bcl-xL, XIAP were determined by quantitative RT-PCR and were normalized to control. b Protein levels of CTGF, Cyr61, MCL, MDR, Survivin, Bcl-xL, XIAP were confirmed by Western blot. Data are representative of at least three independent experiments. Error bars represent SD. **P < 0.01 compared with control

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