Fig. 2
From: circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a
circGFRA1 is upregulated and correlated with poor clinical outcomes in TNBC. a. The expression level of circGFRA1 was determined by qRT-PCR in 11 different mammary cell lines, including two HME cell line (MCF-10A and 184A1) and nine breast cancer cell lines. circGFRA1 expression was normalized using β-actin expression. b. The expression level of circGFRA1 in 51 TNBC tissues and their matched normal adjacent tissues was determined by qRT-PCR. c. OS curves for 222 TNBC patients with high or low circGFRA1 expression. d. DFS curves for 222 TNBC patients with high or low circGFRA1 expression. All the data are shown as the mean ± s.e.m.