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Table 1 Clinicopathological variables and circGFRA1 expression in 222 breast cancer patients

From: circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

Variables Cases (n = 222) circGFRA1 P value
Low High
Age (years)       0.216
  ≤ 50 148 73 49.3% 75 50.7%  
  > 50 74 30 40.5% 44 59.5%  
menopause       0.738
 no 131 62 47.3% 69 52.7%  
 yes 91 41 45.1% 50 54.9%  
Tumor size (cm)       0.029*
  ≤ 2 70 40 57.1% 30 42.9%  
  > 2 152 63 41.4% 89 58.6%  
TNM Staging       <0.001*
 I-II 155 93 60.0% 62 40.0%  
 III-IV 67 10 14.9% 57 85.1%  
LN Infiltrated       <0.001*
 No 117 87 74.4% 30 25.6%  
 Yes 105 16 15.2% 89 84.8%  
Histological grade       0.036*
 Well differentiated 2 2 100.0% 0 0.0%  
 Moderately differentiated 109 57 52.3% 52 47.7%  
 Poorly differentiated 111 44 39.6% 67 60.4%  
  1. *P < 0.05, statistically significant