Fig. 3

SHCBP1 was associated with the invasive and metastatic potential of SS. a Representative micrographs of the motility of SHCBP1-overexpressing or SHCBP1-silencing cells in the wound healing assay at 0 h and 24 h compared to untreated and vector control cells. b, c and d Representative micrographs and quantification of the invasiveness of SHCBP1-overexpressing or SHCBP1-silencing cells in the transwell migration and invasion assays compared to untreated and vector control cells. e SHCBP1 increased the expression of MMP-2 and MMP-9 in SS cells. Error bars represent mean ± SD from three independent experiments, ** p < 0.01