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Table 2 Univariate and multivariate Cox regression of TAGLN2 expression for overall survival in glioma patients

From: TAGLN2 is a candidate prognostic biomarker promoting tumorigenesis in human gliomas

Variable

Univariate Cox Regression

Multivariate Cox Regression

HR (95% CI)

p

HR (95% CI)

p

Age

Increasing years

1.038 (1.023–1.054)

<0.001

0.993 (0.975–1.011)

0.446

Gender

Female vs male

0.847 (0.600–1.195)

0.345

  

WHO grade

High- vs low-

5.840 (4.015–8.494)

<0.001

3.128 (1.969–4.971)

<0.001

TAGLN2 expression

High vs low

2.121 (1.843–2.442)

<0.001

1.713 (1.384–2.119)

<0.001

IDH1 status

Mutation vs wild-type

0.256 (0.178–0.368)

<0.001

0.869 (0.501–1.510)

0.619

Radiotherapy

Yes vs no

0.429 (0.296–0.622)

<0.001

0.439 (0.303–0.638)

<0.001