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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

Fig. 1

The expression of MYC was upregulated in bladder cancer tissues and cells, and siRNA was able to knockdown the expression of this gene in cells. (a) qRT-PCR was used to detect the expression of MYC in bladder cancer tissues. ΔCTN means comparative CT in normal tissue. ΔCTC represents comparative CT in tumor tissue. (b, c) Compared with the negative control, the expression of MYC mRNA was significantly increased in bladder cancer tissues (b, P < 0.01), bladder cancer cell lines T24 and 5637 (C, P < 0.01). (d) The mRNA expression level of MYC was statistically decreased after transfection of si-MYC in T24 and 5637 cells (both P < 0.01). (e, f) The protein expression level of MYC was statistically decreased after transfection of si-MYC in T24 (e) and 5637 (f) (both P < 0.01). All data are shown as the mean ± SD (*p < 0.05, **p < 0.01); bar, SD

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