Fig. 7
From: CLDN6 promotes chemoresistance through GSTP1 in human breast cancer
CLDN6 conferred chemoresistance through GSTP1 on TNBC Hs578t cells. a RT-qPCR verified CLDN6 overexpression in MDAMB231 and Hs578t cells. b IC50 of ADM when overexpressed CLDN6 in MDAMB231 and Hs578t cells. c GSTP1 expression when CLDN6 overexpressed in MDAMB231 and Hs578t cells. d GST activity was measured when CLDN6 overexpressed. e Silencing GSTP1 was verified by western blot in Hs578t/CLDN6 cells. f IC50 of ADM when silenced GSTP1 expression in Hs578t/CLDN6 cells. *,PÂ <Â 0.05; **, PÂ <Â 0.01