Fig. 1

Cytotoxic effects of LIUS and DOX on OSCC cells. Cytotoxic effects were measured by MTT assay after exposure to different ultrasound intensities (a) and different DOX dosage (b) for 24 h. Data are expressed as means ± SD of three independent experiments. c, The morphological and ultra-structural changes of SAS cancer cells were detected by SEM (upper panel) and TEM (lower panel), at different incubation times after 1 W/cm2 ultrasound exposure