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Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Fig. 9

ACTN4 predicts a poor survival and basal-like breast cancer phenotype. (A) ACTN4 is overexpressed in breast tumor tissues (T) compared with the tumor adjacent normal (TAN) breast epithelial tissues from the same patient analyzed by the TMA assay, and ACTN4 was significantly correlated with the breast cancer stage; (B) Data analysis from the TCGA database implied that ACTN4 mRNA predicted a poor overall survival (OS) (a) and disease free survival (DFS) (b) in the 1098 breast cancer patients; (C) ACTN4 expression was significantly elevated in the metastatic phenotypes (P = 0.0443, *P < 0.05) and (D) the TNBC patients (38%)

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