Fig. 2

Identification of cisplatin responsive PIK3CA regulator in resistant cells: a Flow-chart of DNA-protein pulldown assay performed with nuclear extracts of pre and post cisplatin treated A2780-CisR cells. b&c. Identified protein signatures were functionaly categorised using GSEA server. Only transcription factors and their associated partner proteins were used for further analysis. d&e. potential binders were grouped from mutually inclusive or exclusive hits from untreated and treated A2780-CisR cells using Venn 2.1.0 server. Ten top scoring factors from each category were listed in the representative boxes. The complete list is given in the Additional file 1: Table S1-S3