Table 1 Gene expression profiling after ID1 silenced in MHCC97H cells based on PCR array
Functional gene groups | Symbol | Uni.Gene | RefSeq | Descrption | Fold Change |
|---|---|---|---|---|---|
Metabolism | ACLY | Hs.387567 | NM_001096 | ATP citrate lyase | 3.03 |
|  | G6PD | Hs.461047 | NM_000402 | Glucose-6-phosphate dehydrogenase | −9.80 |
Apoptosis | BIRC3 | Hs.127799 | NM_001165 | Baculoviral IAP repeat containing 3 | 3.88 |
|  | CASP2 | Hs.368982 | NM_032982 | Caspase 2, apoptosis-related cysteine peptidase | −2.22 |
Hypoxia | CA9 | Hs.63287 | NM_001216 | Carbonic anhydrase IX | 8.44 |
| Â | EPO | Hs.2303 | NM_000799 | Erythropoietin | 2.30 |
|  | HMOX1 | Hs.517581 | NM_002133 | Heme oxygenase (decycling) 1 | −2.94 |
Cell Senescence | IGFBP3 | Hs.450230 | NM_000598 | nsulin-like growth factor binding protein 3 | 2.81 |
|  | IGFBP5 | Hs.607212 | NM_000599 | Insulin-like growth factor binding protein 5 | −2.56 |
| Â | SERPINB2 | Hs.594481 | NM_002575 | Serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 4.69 |
Cell Senescence | TBX2 | Hs.531085 | NM_005994 | T-box 2 | −2.50 |
Angiogenesis | SERPINF1 | Hs.532768 | NM_002615 | Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.33 |