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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations

Fig. 4

Site-preferred recurrence of tumor somatic mtDNA mutations. a Recurrent times of top 10 mtDNA Positions. b Recurrent mutation rate, which was defined as the total recurrent times of mutations divided by bp length of region, in non-coding and coding regions. Chi-square test was used. c The proportion of nonsynonymous and synonymous mutations in recurrent mutations and singletons. d The heteroplasmic level of recurrent mutations and singletons

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