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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations

Fig. 5

Codon-specific selection on tumor somatic mtDNA mutations. a The correlation between numbers of mutation-caused codon from observed and simulated data. Red circles showed 4 codons which were significantly deviated from trend line. b Residuals and standardized residuals of four outliers in (a) were shown. c Heteroplasmic level of mutation-caused codons. Mean ± SEM, t test was used

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