Fig. 2

miR-150 enhances the sensitivities of NKTL cells to IR in vitro. a qRT-PCR analysis of miR-150 in NK-92 and Hank-1 NKTL cells after overexpression of miR-150 (*P < 0.01 vs miR-150 group ) (Student’s t-test). b MTT assay showed overexpression of miR-150 in NK-92 and Hank-1 cells had no impact on the proliferative activity. Data are expressed as absorbance (Post Hoc test of ANOVA). c The percentages of viable cells of NK-92 and Hank-1 cells transfected with miR-150 compared with negative control, which were exposed to IR as indicated for 72 h by MTT assay (*P < 0.01 vs control group after 10 Gy radiation) (Post Hoc test of ANOVA). d miR-150 enhanced the growth inhibition of NKTL cells exposed to IR in vitro. miR-150 transfected and miR-control cells were treated with IR at the indicated doses of IR for 15 days. The colonies were stained and counted, and survival curves were constructed from three independent experiments (Kruskal-Wallis test). (^#P < 0.05 / ^*P < 0.01 vs control group after 10 Gy radiation)