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Table 1 Correlation between PSAT1 expression and the clinicopathological features of ER-negative breast cancers

From: PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

Characteristics

NO

PSAT1 expression

P-value

(n = 297)

Negative

Positive

 

Age

 < 50

165

64 (38.79)

101 (61.21)

0.546

 ≥ 50

132

46 (34.85)

86 (65.15)

 

Tumor size

 ≤ 2 cm

105

48 (45.71)

57 (54.29)

0.024

 > 2 cm

192

62 (32.29)

130 (67.71)

 

LNM

 Negative

144

55 (38.19)

89 (61.81)

0.719

 Positive

153

55 (35.95)

98 (64.05)

 

TNM stage

 I

62

31 (50.00)

31 (50.00)

0.026

 II;III

235

79 (33.62)

156 (66.38)

 

Histological grade

 I;II

145

38 (26.21)

107 (73.79)

<0.001

 III

152

72 (47.37)

80 (52.63)

 

Her-2 status

 Negative

239

92 (38.49)

147 (61.51)

0.363

 Positive

58

18 (31.03)

40 (68.97)

 

Ki67 status

 Negative

111

63 (56.76)

48 (43.24)

<0.001

 Positive

186

47 (25.27)

139 (74.73)

 

P53 status

 Negative

95

33 (34.74)

62 (65.26)

0.608

 Positive

202

77 (38.12)

125 (61.88)

 
  1. LNM lymph node metastasis