Fig. 7
From: Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel
miR-193a-5p, Bach2 and HO-1 coordinate docetaxel-induced apoptosis in PC3 cells. a PC3 cells were transfected with miR-193a-5p mimic or Ctl mimic and then treated with or without Doc, and HO-1, Bach2 and cleaved caspase-3 were detected by Western blotting. Bottom panel shows densitometric analysis of three independent experiments. *P < 0.01, **P < 0.01, ***P < 0.001 vs. their corresponding control. b Western blotting detected HO-1, Bach2 and cleaved caspase-3 in PC3 cells transfected with anti-miR-193a-5p or Anti-miR-Ctl and then treated with or without Doc. Bottom panel shows densitometric analysis of three independent experiments. *P < 0.01, **P < 0.01, ***P < 0.001 vs. their corresponding control. c Western blotting detected HO-1, Bach2 and cleaved caspase-3 in PC3 cells transfected with the indicated RNA constructs. Right panel shows densitometric analysis of three independent experiments. *P < 0.01 vs. their corresponding control