Table 4 Top 20 enriched pathways of 55 genes within network
Feature ID | Name | Data source | Genes | P Value |
|---|---|---|---|---|
WP366 | TGF beta Signaling Pathway | WIKIPATHWAYS | APP ATF2 EP300 FOSB HDAC1 MYC PTK2 SP1 TP53 | 4.97E-07 |
WP138 | Androgen receptor signaling pathway | WIKIPATHWAYS | EP300 HDAC1 KAT5 MDM2 PTK2 RELA SP1 | 4.27E-06 |
path:hsa05202 | Transcriptional misregulation in cancer | KEGG | CEBPB HDAC1 MDM2 MYC PTK2 RELA SP1 TP53 | 2.02E-05 |
WP2377 | Integrated Pancreatic Cancer Pathway | WIKIPATHWAYS | APP EGR1 EP300 HNF4A MDM2 MYC SP1 TP53 | 3.49E-05 |
path:hsa05169 | Epstein-Barr virus infection | KEGG | ATF2 CD44 EP300 HDAC1 MDM2 MYC RELA TP53 | 4.12E-05 |
path:hsa05030 | Cocaine addiction | KEGG | ATF2 FOSB MAOB RELA SLC18A2 | 1.33E-04 |
REACT_169274 | Cellular Senescence | REACTOME | CEBPB MDM2 RELA SP1 TERF1 TP53 UBC | 3.43E-04 |
path:hsa05031 | Amphetamine addiction | KEGG | ATF2 FOSB HDAC1 MAOB SLC18A2 | 4.35E-04 |
REACT_169325 | Oncogene Induced Senescence | REACTOME | MDM2 SP1 TP53 UBC | 4.68E-04 |
REACT_120734 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | REACTOME | HDAC1 MYC SP1 UBC | 1.00E-03 |
path:hsa05220 | Chronic myeloid leukemia | KEGG | HDAC1 MDM2 MYC RELA TP53 | 1.00E-03 |
REACT_120956 | Cellular responses to stress | REACTOME | CEBPB EP300 MDM2 RELA SP1 TERF1 TP53 UBC | 1.00E-03 |
WP1984 | Integrated Breast Cancer Pathway | WIKIPATHWAYS | EP300 HDAC1 MDM2 MYC SP1 TP53 | 1.00E-03 |
WP254 | Apoptosis | WIKIPATHWAYS | IGF2 MDM2 MYC RELA TP53 | 1.00E-03 |
REACT_121061 | Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | REACTOME | HDAC1 MYC SP1 UBC | 1.00E-03 |
path:hsa05166 | HTLV-I infection | KEGG | ATF2 EGR1 EP300 KAT5 MYC RELA TP53 | 2.00E-03 |
WP399 | Wnt Signaling Pathway and Pluripotency | WIKIPATHWAYS | CD44 EP300 MMP7 MYC TP53 | 2.00E-03 |
REACT_118780 | NOTCH1 Intracellular Domain Regulates Transcription | REACTOME | EP300 HDAC1 MYC UBC | 2.00E-03 |
REACT_299 | Signaling by NOTCH | REACTOME | EP300 HDAC1 MYC TP53 UBC | 3.00E-03 |
h_arfPathway | Tumor Suppressor Arf Inhibits Ribosomal Biogenesis | BIOCARTA | MDM2 MYC TP53 | 3.00E-03 |