Fig. 1

LXA4 inhibits migration and invasion of pancreatic cancer cells. a Wound-healing assays were performed to evaluate the migration of Panc-1 and MIA PaCa-2 cells. At 0 hour, cells were treated with either vehicle (methanol) or LXA4 (400 nM), and photographs were taken at 0 and 24th hour. The original borders were marked with red lines. b and c The two cell lines treated by vehicle or LXA4 were seeded into matrigel-coated chambers to perform transwell assays and the numbers of passed cells were counted in 10 random fields under 200× magnification at 0 and 24th hour. *, P < 0.05. All data were obtained from at least three independent experiments