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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: RETRACTED ARTICLE: Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice

Fig. 5

Effects of A-769662 added to the pre-Cur on autophagic and apoptotic status in HCT116 cells. a. Immunofluorescent images. Hoechst 33,342 staining (blue) indicates nucleus and Cyto-ID Green staining (green) autophagy status. b. Western blot analysis of beclin-1, p62 and LC3II/LC3I. c. Comparison of viability of colon cancer HCT116 cells. d. Western blots analysis of cleaved-caspase-3. *, p < 0.05, **, p < 0.01, and ***, p < 0.001

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