Fig. 7
From: PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT
Expression of GOLM1 correlates with p-PDGFRα. a Relative expression levels of GOLM1 in different glioma molecular subtypes (classical, mesenchymal, neural, and proneural) and normal brain tissue samples using the publicly available data from TCGA. Correlation between GOLM1 and PDGFRA in gliomas determined using TCGA (b) and Rembrandt datasets c. The statistical significance of correlation was evaluated using a linear regression model (TCGA all gliomacor = 0.261, P < 0.001; Rembrandt all gliomacor = 0.433, P < 0.001). d IHC staining of p-PDGFRα and GOLM1 protein in primary human GBM samples. Representative images and magnified inset are labeled as GBM 1 and GBM 2. Scale bar = 200 μm