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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence

Fig. 2

MCM6 enhances HCC cell migration, invasion and proliferation properties in vitro. a Expression of MCM6 in hepatocellular carcinoma cell lines analyzed by qRT-PCR and western blotting. b-c Expression levels of MCM6 were measured by qRT-PCR, western blot and immunofluorescence in HCC cells treated with LV-shMCM6 or LV-Scramble. d Representative images and quantification of the number of cells that migrated or invaded in the indicated stable cell lines. Experiments were repeated three times with similar results, and error bars represent the mean ± SEM, ***P < 0.001. e Wound-healing assays were employed to detect the migration capacity of MCM6-altered cells. The in vitro proliferation function of MCM6 was measured by the CCK8 assay (f), colony-forming assay (g) and Edu assays (h)

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