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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia

Fig. 1

High expression levels of INPP4B in leukemia cells with the NPM1 mutation. a RNA-seq mRNA expression data from the TCGA database were used to compare INPP4B expression between AML patients with (n = 41) and without NPM1 mutation (n = 130). * p < 0.05. b The mRNA levels of INPP4B in primary NPM1-mutated AML cases (n = 14) were assessed by qRT-PCR, and compared to NPM1-unmutated AML cases (n = 22). c qRT-PCR analysis of INPP4B mRNA expression from the indicated myeloid leukemia cell lines. d Western blotting analysis of INPP4B and β-actin (as a loading control). Data were represented as mean ± s.d. of three individual experiments

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