Table 1 Clinical Characteristics of Newly Diagnosed AML Patients
From: INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia
| Characteristics | Median (range) | No. of cases |
|---|---|---|
| Sex | ||
| Female | 19 | |
| Male | 17 | |
| Total | 36 | |
| Age | ||
| Median, years | 53.8 (26–79) | |
| WBC | ||
| Median, ×109/L | 44 (0.3–295.0) | |
| Platelets | ||
| Median, ×109/L | 57.3 (3.0–655.0) | |
| AML FAB subtype | ||
| AML without maturation: M1 | 4 | |
| AML with maturation: M2 | 6 | |
| Acute promyelocytic leukemia: M3 | 9 | |
| Acute myelomonocytic leukemia: M4 | 7 | |
| Acute monoblastic or monocytic leukemia: M5 | 9 | |
| Other subtype | 1 | |
| Karyotype | ||
| Normal | 14 | |
| t (8;21) | 5 | |
| t (15;17) | 6 | |
| inv. (16) | 7 | |
| Unknown | 4 | |
| Gene mutations | ||
| NPM1 | 14 | |
| FLT3-ITD | 10 | |
| WT1 | 9 | |
| CBFB-MYH11 | 5 | |