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Table 1 Clinical Characteristics of Newly Diagnosed AML Patients

From: INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia

Characteristics Median (range) No. of cases
Sex
 Female   19
 Male   17
 Total   36
Age
 Median, years 53.8 (26–79)  
WBC
 Median, ×109/L 44 (0.3–295.0)  
Platelets
 Median, ×109/L 57.3 (3.0–655.0)  
AML FAB subtype
 AML without maturation: M1   4
 AML with maturation: M2   6
 Acute promyelocytic leukemia: M3   9
 Acute myelomonocytic leukemia: M4   7
 Acute monoblastic or monocytic leukemia: M5   9
 Other subtype   1
Karyotype
 Normal   14
 t (8;21)   5
 t (15;17)   6
 inv. (16)   7
 Unknown   4
Gene mutations
NPM1   14
FLT3-ITD   10
WT1   9
CBFB-MYH11   5
  1. Abbreviations: AML acute myeloid leukemia, WBC white blood cell; FAB classification, French-American-British classification, a classification of acute leukemia produced by three-nation joint collaboration