Fig. 2
From: Stress-inducible Protein-1 promotes metastasis of gastric cancer via Wnt/β-catenin signaling pathway
STIP1 promoted cells migration and invasion. a SGC7901 and AGS cells were treated with STIP1 or not for 48 h, and the mesenchymal morphological alterations were observed in both cells with overexpression of STIP1. b After transfected with siRNA targeted STIP1 (siSTIP1#1, siSTIP1#2), the distance was longer than that in control cells (siCtrl). After overexpression of STIP1, the distance was shorter than that in control cells (Vector). c After transfected with siRNA targeted STIP1, the migration and invasion abilities were significantly decreased than that in control cells. After overexpression of STIP1, the migration and invasion abilities were significantly increased than that in control cells. d After transfected with siRNA targeted STIP1, the expressions of MMPs (MMP2, MMP7, and MMP9) were reduced than that in control cells. After overexpression of STIP1, the expressions of MMPs (MMP2, MMP7, and MMP9) were elevated than that in control cells. *p < 0.05, **p < 0.01, ***p < 0.001