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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Stress-inducible Protein-1 promotes metastasis of gastric cancer via Wnt/β-catenin signaling pathway

Fig. 6

Inhibition of Wnt/β-catenin signaling pathway could not totally abolish STIP1-mediated cells’ migration and invasion abilities. a PNU-74654 effectively decreased the expression levels of p-β-catenin(Tyr654), c-Myc, Cyclin D1, as well as N-cadherin and vimentin, and increased the expression level of E-cadherin by Western blot. b Treated with/without PNU-74654, the migration number of cells in STIP1-overexpression group was increased than that of control group. c Treated with/without PNU-74654, the invasion number of cells in STIP1-overexpression group was increased than that of control group. *p < 0.05

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