Fig. 3

Reversed correlations of miR-32-5p and PTEN. a, b miR-32-5p is up-regulated but PTEN is down-regulated in 44 HCC specimens, compared with 28 unpaired para-carcinoma liver tissues. P Ca, paracarcinoma liver tissues. The miR-32-5p and PTEN levels were calculated using the corresponding inner control U6 and GAPDH respectively, **p < 0.01 by non-parametric Mann-Whitney-Wilcoxon test. c Reversed correlations of miR-32-5p and PTEN in HCC patients’ tissues, by Pearson’s correlation test. d-g High miR-32-5p or low PTEN in 44 HCC patients predicts shorter OS and PFS, by Kaplan-Meier analysis. OS, overall survival, PFS, progression-free survival. h-k miR-32-5p is up-regulated but PTEN is down-regulated in both paired and un-paired HCC and paracarcinoma liver specimens in TCGA dataset. *p < 0.05, **p < 0.01, ***p < 0.001 by non-parametric Mann-Whitney-Wilcoxon test