Fig. 7
Antitumor activity of CP-EPS8-NLS in a U937 xenograft model. a U937 cells (5 × 106 per flank) were injected into the right flank of mice. When the volume of tumors reached 100 mm3, the mice were randomly divided into two groups (7 mice in each group). Then, PBS or CP-EPS8-NLS were intraperitoneally injected into the mice every other day. b The volume of each tumor was measured every other day for 22 days. c Body weight of the mice. d The volume of each tumor was measured after tumor extraction from the mice at the experimental endpoint. e Image of tumors excised from mice after 22 days of treatment. f EPS8 and Ki67 in tumor tissues at the end of the experiments using IHC staining