Fig. 6

The OSC inhibitory effect of EGCG targeting SOX2OT V7 is partly achieved by restrain of Notch3 / DLL3 signaling. To illustrate whether the OSC inhibitory effect of EGCG targeting SOX2OT V7 is partly achieved by mediating of Notch signaling, relative mRNA levels of target genes, receptors and ligands of Notch signaling were detected using qRT-PCR in V7 overexpressed OSCs with or without EGCG treatment a.^a p < 0.05 vs. parental cells (Con), ^aa p < 0.01 vs. parental cells (Con), ^bp < 0.05 vs. control lentivirus infected OSCs (Lv-con).b Typical pictures of nude mice with tumorigenicity which were under different treatments. c Typical pictures of stripped tumors derived from mice in different treatment groups