Fig. 3
From: MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development
MYL6B is overexpressed in HCC and linked to bad prognosis. (a, b) Total protein extraction from HCC tissues, paired non-tumor adjacent tissues and HCC cell lineswere subject to immunoblotting with MYL6B and GAPDH antibodies. (c, d) The mRNA expression level of MYL6B in HCC tissues, paired non-tumor adjacent tissues based on RNA sequencing data (RNA-seq) from the TCGA database and its’ correlation with patient prognosis. (e, f) The mRNA expression level of MYL6B in HCC tissues, paired non-tumor adjacent tissues based on real time PCR analysis of Guilin Cohort (35 patients) and its’ correlation with patient prognosis