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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells

Fig. 5

Up-regulation of miR-17 and miR-106b were associated with clinicopathologic factors. a c-Myc, miR-17 and miR-106b were significantly up-regulated in 30 human HCC tissues compared with the corresponding non-tumor tissues. The statistical differences were analyzed using the paired t-test. The horizontal lines in the box plots represented the median, the boxes represented the interquartile range, and the whiskers represented the 5th and 95th percentiles. b Correlation among the expression status of c-Myc, miR-17 and miR-106b. c and d Kaplan-Meier analyses of the correlations between the miR-17 expression level and the (c) recurrence-free survival or (d) overall survival of 30 HCC patients. e-f Kaplan-Meier analyses of the correlations between the miR-106b (e) recurrence-free survival or (f) overall survival of 30 HCC patients. The survival curves were compared using a Long-rank test

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