Fig. 1

Lower expression of CADM2 was observed in HCC samples. a Analysis GEO data (GSE27150) of CADM2 expression levels in HCC and adjacent normal tissues (n = 57). b Kaplan-Meier analysis of median overall survival of patients with different CADM2 expression Kaplan-Meier analysis of median overall survival of patients with different CADM2 expression levels from GEO database (GSE27150, P = 0.0757, Red: High expression CADM2, Blue: Low expression CADM2). c Analysis GEO data (GDS3091) of CADM2 expression levels in HCC patients with venous metastasis (n = 9) and without venous metastasis (n = 11) from GEO data (GDS3091) were analyzed. d Relative CADM2 expression levels in HCC samples were detected by qRT-PCR. (n = 36, P = 0.0226). e CADM2 expression in HCC samples was examined using western blotting. GAPDH was used as a loading control. f qRT-PCR for detecting CADM2 mRNA expression levels in several liver cell lines as indicted. (*P < 0.05; **P < 0.01)