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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Development and evaluation of novel tumor-targeting paclitaxel-loaded nano-carriers for ovarian cancer treatment: in vitro and in vivo

Fig. 4

The cellular toxicity of two kinds of nano-carriers in vitro

. Notes: (a) The toxicity of the blank PEG-PLA-NP to SK-OV-3 cells. Up to the concentration of 100 μg/ml, blank nano-carriers did not inhibit the SK-OV-3 cells viability significantly; (b) The cellular inhibition rate in different groups. PTX-PEG-PLA-FA-NP showed significantly more toxicity against SK-OV-3 cells at multiple dosages than PTX-PEG-PLA-NP as well as free PTX based on the equivalent PTX concentrations (p < 0.05). (c)The toxicity to SK-OV-3 cells under different co-incubation intervals. *p < 0.05, **p < 0.01, ***p < 0.001 vs PTX. #p < 0.05, # #p < 0.01, # # #p < 0.001 vs PTX-PEG-PLA-NP

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