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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Development and evaluation of novel tumor-targeting paclitaxel-loaded nano-carriers for ovarian cancer treatment: in vitro and in vivo

Fig. 7

Anti-tumor effect of free PTX, PTX-PEG-PLA-NP and PTX-PEG-PLA-FA-NP solutions to the nude mice with subcutaneous tumor. Notes: (a) Established subcutaneous tumor models in nude mice; (b) Tumor tissues removed from the mice at the end point in different groups; (c) Tumor growth curves throughout the whole experiment. The inhibitory rates was 41.88% in the PTX-PEG-PLA-FA-NP group, which was 1.5 times higher than that in PTX-PEG-PLA-NP group (28.02%) and free PTX group (25.99%); (d) Body weight change of tumor-bearing mice. There was no significant difference in the average body weights among four groups (p > 0.05), which means no obvious side effects of nano-carriers system

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