Table 1 Potential LIR Motif in ALK
No | Position | Domain | Type | Sequence |
|---|---|---|---|---|
1 | 46–49 | Extracellular | Y | YSRL |
2 | 253–256 | Extracellular | F | FPFL |
3 | 290–293 | MAM1 | W | WRRI |
4 | 320–323 | MAM1 | F | FLLL |
5 | 386–389 | MAM1 | W | WTVL |
6 | 419–422 | MAM1 | F | FFAL |
7 | 587–590 | MAM2 | Y | YEGL |
8 | 595–598 | MAM2 | W | WMVL |
9 | 625–628 | MAM2 | F | FDNI |
10 | 635–638 | MAM2 | Y | YLTI |
11 | 772–775 | Extracellular | Y | YILV |
12 | 1052–1055 | TM | F | FSGI |
13 | 1127–1130 | PTK | F | FGEV |
14 | 1193–1196 | PTK | F | FILL |
15 | 1315–1318 | PTK | F | FGVL |
16 | 1376–1379 | PTK | F | FAII |
17 | 1401–1404 | Intracellular | Y | YGPL |