Fig. 3

Lipidomics analysis for HCT116 cells transfected with shSCD1 or shNC. a Volcano plots show log2 fold-changes versus −log10 P-values of lipid species of HCT116 transfected with shSCD1 when compared with control cells. The horizontal line indicates the cut-off value for significance levels. Each dot represents a lipid species (red: lipid species P < 0.05 with a > 2 fold-change; grey: not significant). b-d Relative abundance of lipids extracted from shSCD1 or shNC-transfected HCT116 cells, including PE (b), MG (c) and TG (d)