Fig. 7

PTEN plays an important role in SCD1-induced migration and invasion of CRC cells. a, b Representative Western blot and quantification data of PTEN proteins of OA-treated HCT116 (a) and Caco2 (b) cells. c Representative Western blot and quantification data of PTEN in HCT116 cells transfected with siRNAs for PTEN (si1 and si2) or Caco2 cells ectopically expressing PTEN. d Representative photographs of transwell assays of shSCD1 or shNC-transfected HCT116 after being transfected with PTEN siRNAs (siPTEN) or negative control scramble siRNAs (siNC). The scale bar is 100 μm. e, f Histograms show the numbers of migrated (e) and invasive (f) HCT116 cells. g Transwell assay of SCD1 overexpression Caco2 cell lines after ectopically expressing PTEN. The scale bar is 100 μm. h, i Histograms show the number of migrated (h) and invasive (i) Caco2 cells